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Natural Frozen Embryo Transfer (Nat FET) Protocol

Your treatment plan will be submitted to FCNE’s insurance team once all of the ordered testing isresulted and valid consents are on file.Please note that the insurance approval process can take up to 21 business days.Once approved, you will be notified via the portal. The clinical team will then begin to work on themedication order within 72 hours. Please note that in most cases Prior Authorization is required(PA). The time from medication order to delivery to your home could take up to 10-14 days.Please note that a cycle can’t be started until you have received all of the medications.

Instructions

1. Call your Care Team (1-781-944-0052) on cycle day one of your period. A full
flow period before 3:00 p.m. is considered cycle day one. Abstain from
unprotected intercourse day one of menses until after you have the
pregnancy test at the end of your cycle


2. You will be instructed to return to the office for cycle day 2 for blood work and
vaginal ultrasound. The doctor will review your ultrasound and blood work to
determine when you will return for more monitoring.


3. You will get portal instructions that afternoon to start the injectable gonadotropin
(Gonal-F or Follistim). The physician may also opt to have you take estrace.


4. The physician will review labs and continue monitoring to determine dominant
follicle and or endometrium of 7-8mm. This may be daily or every other day.


5. If ordered by your physician, the hCG trigger will occur with a dominant follicle of
at least 18mm and/or the beginning of an LH surge. If no hCG was ordered, then
an LH level > 10 will be considered a surge.

6. The embryo transfer (ET) will be scheduled five days after the calculated day of
ovulation. Please be aware that it is the policy of FCNE that children are not
allowed in the Procedure Suite on the second floor for IVF egg retrievals
and embryo transfers.


7. Azythromycin 250 mg 5 day dose pack OR Doxycycline 100mg tablets by mouth
for 4 days will start on the day of ovulation.


8. Progesterone in oil injections will start as instructed and continued with
pregnancy.

 

Please take morning injectable medications at a time that works with your morning schedule
within a 2-hour time frame from day to day.

Please take evening injectable medications between 7 – 9 PM within a 2-hour time frame from
day to day. If there is a day that you have plans to be out in the evening it is better to take the
injection earlier before you go out.
The trigger injection (Human Chorionic Gonadatropin, Pregnyl) will be injected at a time specified
by FCNE and will be included in your instructions.

9. You will be instructed to arrive with a full bladder 15 minutes before your
scheduled embryo transfer. You can eat and drink that morning unless
otherwise instructed. Once the embryo transfer is complete, you will be
discharged to your home with instructions to rest that day.


10. The pregnancy test will be scheduled 10 days after the embryo transfer.

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