Frozen Embryo Transfer (Letrozole) Protocol
Your treatment plan will be submitted to FCNE’s insurance team once all of the ordered
testing is resulted and valid consents are on file.
Please note that the insurance approval process can take up to 21 business days.
Once approved, you will be notified via the portal. The clinical team will then begin to
work on the medication order within 72 hours. Please note that in most cases Prior
Authorization is required (PA). The time from medication order to delivery to your home
could take up to 10-14 days.
Please note that a cycle can’t be started until you have received all of the medications.
Instructions
1. Call your Care Team (1-781-944-0052) on cycle day one of your period. A full
flow period before 3:00 p.m. is considered cycle day one. Abstain from
unprotected intercourse day one of menses until after you have the
pregnancy test at the end of your cycle
2. You will return on cycle day 2 for blood and ultrasound.
3. You will get portal instructions regarding the Letrozole.
4. You will be instructed to return to the office for cycle day 10 for blood work and
vaginal ultrasound. The doctor will review your ultrasound and blood work to
determine when you will return for more monitoring.
5. You will get portal instructions that afternoon.
6. The physician will review labs and continue monitoring to determine ovulation.
This may be daily or every other day.
7. If ordered by your physician, the hCG trigger will occur with a dominant follicle of
at least 18mm and/or the beginning of an LH surge. If no hCG was ordered then
an LH level > 10 will be considered a surge.
8. An estimation of ovulation will be made based on the LH surge or hCG
administration. The embryo transfer (ET) will be scheduled five days after the
calculated day of ovulation. Please be aware that it is the policy of FCNE that
children are not allowed in the Procedure Suite on the second floor for IVF
egg retrievals and embryo transfers.
9. Azythromycin 250 mg 5 day dose pack OR Doxycycline 100mg tablets by mouth
for 4 days will start on the day of ovulation.
10. You will be instructed to arrive with a full bladder 15 minutes before your
scheduled embryo transfer. You can eat and drink that morning unless otherwise
instructed. Once the embryo transfer is complete, you will be discharged to your
home with instructions to rest that day.
11. Either Progesterone in oil injections or Crinone will start as instructed and
continued with pregnancy.