Frozen Embryo Transfer (FET) Protocol
Your treatment plan will be submitted to FCNE’s insurance team once all of the ordered testing is
resulted and valid consents are on file.
Please note that the insurance approval process can take up to 21 business days.
Once approved, you will be notified via the portal. The clinical team will then begin to work on the
medication order within 72 hours. Please note that in most cases Prior Authorization is required
(PA). The time from medication order to delivery to your home could take up to 10-14 days.
Please note that a cycle can’t be started until you have received all of the medications.
Instructions
1. Report cycle day one of your period via the patient portal or 781-944-0052. A full
flow period before 3:00 p.m. is considered cycle day one. Abstain from unprotected intercourse day one of menses until after you have the pregnancy test at the end of your cycle
2. You will be instructed to return to the office for cycle day 2 baseline blood work
and vaginal ultrasound. The doctor will review your ultrasound and blood work to
determine whether it is appropriate to start Estrace supplementation.
3. You will get portal instructions to start Estrace 2 MG orally twice daily.
4. You will return to the office approximately 10 - 14 days later for blood work and a
vaginal ultrasound to evaluate the uterine endometrial lining and progesterone
level.
5. You will get portal instructions that afternoon. If your endometrium is 7-8 mm or
greater, you will be given a start date for Progesterone intramuscular injection
and antibiotic and scheduled for your embryo transfer. The embryo transfer (ET)
will be scheduled for the sixth day of progesterone on a weekday. We do not do
FET on weekends. Please be aware that it is the policy of FCNE that children are not allowed in the Procedure Suite on the second floor for IVF egg retrievals and embryo transfers.
Please take morning injectable medications at a time that works with your morning schedule
within a 2-hour time frame from day to day.
Please take evening injectable medications between 7 – 9 PM within a 2-hour time frame from
day to day. If there is a day that you have plans to be out in the evening it is better to take the
injection earlier before you go out.
The trigger injection (Human Chorionic Gonadatropin, Pregnyl) will be injected at a time specified
by FCNE and will be included in your instructions.
6. If your endometrium is less than 7mm, you will likely continue on estrace 2 mg
and may be increased to three times a day. We may add estrogen patches every
other day as well and repeat blood work and vaginal ultrasound in 3-6 days.
7. You will be instructed to arrive with a full bladder 15 minutes before your
scheduled embryo transfer. You can eat and drink that morning unless otherwise
instructed. Once the embryo transfer is complete, you will be discharged to your
home with instructions to rest that day.
8. Your pregnancy test will be scheduled for 10 days after your Embryo Transfer.